prolia® is proven to help make bones stronger proven to help increase bone density. i take prolia®, it's different. it's two shots a year. do not take prolia® if you have low blood calcium, are pregnant, are allergic to it, or take xgeva® ... get medical help right away for a serious allergic reaction causing low blood pressure; trouble breathing; throat, face, lip, or tongue swelling; or rash, itching or hives. prolia® can cause serious side effects, including low blood calcium, serious infections, which could require hospitalization, and skin inflammation, rash, or eczema. tell your doctor about dental problems, as severe jaw bone problems may happen, or new or unusual pain in your hip, groin or thigh, as unusual thigh bone fractures have occurred.. what's out there matters to me... ...so does what's in here. break a leg! ask your doctor if prolia® is right for you.